Today i had to manually handle the mouse wheel functionality in a customer project and suppress the raising of the MouseWheel event as long as a specific condition returned false.

After some research i found a fairly simple solution:

public const int WM_MOUSEWHEEL = 0×020A;

protected override void WndProc(ref Message m) 

{

     if (m.HWnd != this.Handle)       

     {            

            return;       

     } 

      switch (m.Msg)    

      {           

            case Win32Messages.WM_MOUSEWHEEL:

                  if( ! <your condition goes here> )

                  {

                         return;  

                  }               

                  break;           

            default:               

                  break;       

      }

      base.WndProc(ref m);  

}

Hope this helps!